| Primary Identifier | MGI:1338802 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 20419 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables SH2 domain binding activity. Involved in fibroblast growth factor receptor signaling pathway and regulation of neural precursor cell proliferation. Predicted to be located in cytoplasm; midbody; and spindle. Is expressed in forebrain; forelimb bud; midbrain ventricular layer; nephrogenic zone; and submandibular gland primordium. Orthologous to human SHCBP1 (SHC binding and spindle associated 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit normal viability, fertility and T cell development but show decreased susceptibility to experimental autoimmune encephalomyelitis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
