Primary Identifier | MGI:2685951 | Organism | mouse, laboratory |
Chromosome | 8 | NCBI Gene Number | 244281 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable actin filament binding activity and protein phosphatase binding activity. Involved in neuron projection morphogenesis and phosphatidylinositol 3-kinase/protein kinase B signal transduction. Predicted to be located in cytoplasm and plasma membrane. Predicted to be part of myosin complex. Predicted to be active in nucleoplasm and perinuclear region of cytoplasm. Is expressed in central nervous system; metanephros; and white fat. Orthologous to human MYO16 (myosin XVI). PHENOTYPE: Triple KO of Nyap1, Nyap2 and Myo16 results in decreased brain weight and cortex and striatum size and reduced neurite length in cortical neurons. [provided by MGI curators] |