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Protein Coding Gene : Coprs coordinator of PRMT5, differentiation stimulator
Primary Identifier  MGI:1913673 Organism  mouse, laboratory
Chromosome  8 NCBI Gene Number  66423
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable histone binding activity. Involved in muscle organ development. Acts upstream of or within blastocyst hatching. Predicted to be located in cytosol; nucleoplasm; and plasma membrane. Predicted to be active in nucleus. Is expressed in early conceptus and secondary oocyte. Orthologous to human COPRS (coordinator of PRMT5 and differentiation stimulator).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit reduced retroperitoneal white adipose tissue with fewer and larger adipocytes. In vitro adipogenic conversion of embryoid bodies and primary embryonic fibroblasts is markedly delayed. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA 2410022L05 gene,
  • MGC11316,
  • MGI:1916725,
  • 1700029I03Rik,
  • RIKEN cDNA 1700029I03 gene,
  • AA409325,
  • expressed sequence AA409325,
  • 2410022L05Rik,
  • expressed sequence AI256813,
  • C85432,
  • COPR5,
  • MGI:2142487,
  • MGI:2142413,
  • coordinator of PRMT5, differentiation stimulator,
  • expressed sequence C85432,
  • MGI:2142866,
  • Coprs,
  • AI256813
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