| Primary Identifier | MGI:97851 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 20516 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Enables sodium:phosphate symporter activity. Involved in positive regulation of bone mineralization. Predicted to be located in brush border membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; liver; male reproductive gland or organ; spleen; and yolk sac. Used to study basal ganglia calcification. Human ortholog(s) of this gene implicated in basal ganglia calcification. Orthologous to human SLC20A2 (solute carrier family 20 member 2). PHENOTYPE: Mice homozygous for a knock-out allele exhibit brain calcifications in the thalamus, basal ganglia and cerebral cortex, microgliosis, and a high inorganic phosphate concentration [Pi] in cerebrospinal fluid. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
