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Protein Coding Gene : Ido2 indoleamine 2,3-dioxygenase 2
Primary Identifier  MGI:2142489 Organism  mouse, laboratory
Chromosome  8 NCBI Gene Number  209176
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables indoleamine 2,3-dioxygenase activity. Acts upstream of or within tryptophan catabolic process to kynurenine. Located in cytoplasm. Is expressed in corpus striatum. Orthologous to human IDO2 (indoleamine 2,3-dioxygenase 2).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired T cell function and decreased susceptibility to type IV hypersensitivity reaction. Homozygosity for a catalytically inactive mutant leads to decreased susceptibility to type IV hypersensitivity reaction. [provided by MGI curators]
  • synonyms:
  • indoleamine-pyrrole 2,3 dioxygenase-like 1,
  • Ido2,
  • indoleamine 2,3-dioxygenase 2,
  • AI265623,
  • Indol1,
  • MGC:31194,
  • C230043N17Rik,
  • expressed sequence AI265623,
  • RIKEN cDNA C230043N17 gene
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