Primary Identifier | MGI:2177268 | Organism | mouse, laboratory |
Chromosome | 8 | NCBI Gene Number | 244416 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including [phosphorylase] phosphatase activity; glycogen binding activity; and protein phosphatase 1 binding activity. Predicted to contribute to phosphoprotein phosphatase activity. Involved in positive regulation of glycogen biosynthetic process. Predicted to be located in glycogen granule. Predicted to be part of protein phosphatase type 1 complex. Is expressed in several structures, including alimentary system; genitourinary system; hemolymphoid system gland; respiratory system; and sensory organ. Orthologous to human PPP1R3B (protein phosphatase 1 regulatory subunit 3B). PHENOTYPE: Mice homozygous for a knock-in point mutation exhibit improved glucose tolerance and increased weight loss and serum glucose level in response to a 36 hour fast. [provided by MGI curators] |