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Protein Coding Gene : Glra3 glycine receptor, alpha 3 subunit
Primary Identifier  MGI:95749 Organism  mouse, laboratory
Chromosome  8 NCBI Gene Number  110304
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0)

Predicted to enable excitatory extracellular ligand-gated monoatomic ion channel activity and glycine-gated chloride ion channel activity. Predicted to contribute to extracellularly glycine-gated chloride channel activity. Involved in presynaptic modulation of chemical synaptic transmission. Acts upstream of or within glutamate receptor clustering. Located in GABA-ergic synapse; dendrite; and glutamatergic synapse. Is active in glycinergic synapse and presynaptic membrane. Is expressed in central nervous system and eye. Orthologous to human GLRA3 (glycine receptor alpha 3).
PHENOTYPE: Homozygous null mice are fertile and display decreased inflammatory pain sensitization without any gross abnormalities in the brain or spinal cord. [provided by MGI curators]
  • synonyms:
  • MGD-MRK-10132,
  • Glra3,
  • glycine receptor, alpha 3 subunit
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1 Involved In Mutations

Trail: ProteinCodingGene

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Homology

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Interactions

3 Pathways

Trail: ProteinCodingGene

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

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