Primary Identifier | MGI:2676326 | Organism | mouse, laboratory |
Chromosome | 8 | NCBI Gene Number | 244486 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable metalloendopeptidase activity. Predicted to be involved in male gonad development and proteolysis. Located in external side of plasma membrane and sperm head plasma membrane. Orthologous to human ADAM29 (ADAM metallopeptidase domain 29). PHENOTYPE: Homozygous null mice show reduced weight gain rate and reduced steatosis in response to high-fat feeding. Mice show elevated oxygen consumption, carbon dioxide production, and energy expenditure and enhanced wound healing. [provided by MGI curators] |