| Primary Identifier | MGI:96157 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 97165 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA-binding transcription factor binding activity; cis-regulatory region sequence-specific DNA binding activity; and protein domain specific binding activity. Involved in several processes, including regulation of gene expression; regulation of stem cell proliferation; and response to lipopolysaccharide. Acts upstream of or within several processes, including male gonad development; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; and spermatid nucleus differentiation. Located in several cellular components, including chromatin; extracellular space; and nucleus. Is expressed in several structures, including alimentary system; brain; branchial arch; retina; and urinary system. Orthologous to human HMGB2 (high mobility group box 2). PHENOTYPE: Male mice homozygous for disruptions in this gene display reduced fertility. Female fertility is normal. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
