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Protein Coding Gene : Aadat aminoadipate aminotransferase
Primary Identifier  MGI:1345167 Organism  mouse, laboratory
Chromosome  8 NCBI Gene Number  23923
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable protein homodimerization activity and transaminase activity. Predicted to be involved in 2-oxoglutarate metabolic process; glutamate metabolic process; and kynurenine metabolic process. Located in mitochondrion. Is expressed in several structures, including alimentary system; brain; heart; liver; and metanephros. Orthologous to human AADAT (aminoadipate aminotransferase).
PHENOTYPE: Homozygous null mice are viable and display earlier eye opening and development of air righting and open field crossing responses, and transient hyperactivity and neuronal abnormalities. [provided by MGI curators]
  • synonyms:
  • kynurenine aminotransferase II,
  • MGI:2142647,
  • expressed sequence AI875679,
  • AI875679,
  • KATII,
  • mKat-2,
  • Kyat2,
  • Aadat,
  • Kat2,
  • aminoadipate aminotransferase
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Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

Trail: ProteinCodingGene

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

4 Pathways

Trail: ProteinCodingGene

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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