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Protein Coding Gene : Ddx60 DExD/H box helicase 60

Primary Identifier  MGI:2384570 Organism  mouse, laboratory
Chromosome  8 NCBI Gene Number  234311
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables RNA binding activity. Acts upstream of or within defense response to virus. Located in cytoplasm. Is expressed in lens. Orthologous to human DDX60 (DExD/H-box helicase 60).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit normal immunity to several viruses (IAV, EMCV, SINV) but increased susceptibility to VSV infection. [provided by MGI curators]
  • synonyms:
  • Ddx60,
  • DExD/H box helicase 60,
  • BC013672,
  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 60,
  • MGC:19297,
  • cDNA sequence BC013672

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For