Primary Identifier | MGI:1858422 | Organism | mouse, laboratory |
Chromosome | 8 | NCBI Gene Number | 53978 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables PDZ domain binding activity. Acts upstream of or within G protein-coupled receptor signaling pathway; positive regulation of MAPK cascade; and positive regulation of Rho protein signal transduction. Is active in glutamatergic synapse and presynaptic active zone membrane. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; hemolymphoid system gland; and sensory organ. Orthologous to human LPAR2 (lysophosphatidic acid receptor 2). PHENOTYPE: Animals homozyogous for a targeted mutation appear phenotypically normal. [provided by MGI curators] |