Primary Identifier | MGI:2148775 | Organism | mouse, laboratory |
Chromosome | 8 | NCBI Gene Number | 83984 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables magnesium ion binding activity and protein serine/threonine kinase activity. Involved in flagellated sperm motility; peptidyl-serine phosphorylation; and sperm DNA condensation. Is active in axonemal microtubule doublet inner sheath and sperm flagellum. Orthologous to human TSSK6 (testis specific serine kinase 6). PHENOTYPE: Homozygous null males are infertile and exhibit decreased sperm numbers and sperm motility, abnormal sperm head morphology and reduced DNA compaction in spermatozoa. [provided by MGI curators] |