Primary Identifier | MGI:2384585 | Organism | mouse, laboratory |
Chromosome | 8 | NCBI Gene Number | 234366 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable protein-macromolecule adaptor activity. Acts upstream of or within several processes, including blood vessel development; chordate embryonic development; and embryonic body morphogenesis. Predicted to be located in nucleoplasm. Predicted to be part of NuRD complex. Is expressed in several structures, including brain and enteric nervous system. Orthologous to human GATAD2A (GATA zinc finger domain containing 2A). PHENOTYPE: Mice homozygous for a knock-out allele die around E9.5 displaying variable developmental defects, including malformed or unfused neural folds, failure of closure of anterior neuropore, missing or excessively large blood vessels in the yolk sac, abnormal embryo turning, and embryonic growth arrest. [provided by MGI curators] |