Primary Identifier | MGI:1918847 | Organism | mouse, laboratory |
Chromosome | 8 | NCBI Gene Number | 71597 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Acts upstream of or within negative regulation of intestinal absorption; regulation of transcription by RNA polymerase II; and regulation of vitamin A metabolic process. Predicted to be located in nucleus. Is expressed in several structures, including central nervous system; genitourinary system; gut; liver; and thymus. Orthologous to human ISX (intestine specific homeobox). PHENOTYPE: Homozygous null mice are viable and fertile up to 1 year of age and display no histological abnormalities of the gut. [provided by MGI curators] |