| Primary Identifier | MGI:2443063 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 213435 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables calcium/calmodulin-dependent protein kinase activity and myosin light chain kinase activity. Involved in protein phosphorylation and sarcomere organization. Located in cytoplasm. Colocalizes with actin cytoskeleton. Is expressed in heart atrium; heart ventricle; inner ear; liver; and tibialis anterior. Orthologous to human MYLK3 (myosin light chain kinase 3). PHENOTYPE: Mice homozygous for a knock-out allele exhibit cardiac hypertrophy, reduced cardiac function and increased response of heart to induced stress. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
