Primary Identifier | MGI:1921981 | Organism | mouse, laboratory |
Chromosome | 8 | NCBI Gene Number | 382030 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable protein phosphatase regulator activity. Predicted to be involved in positive regulation of triglyceride biosynthetic process and protein localization to nucleus. Predicted to be located in cytosol and nuclear membrane. Predicted to be part of Nem1-Spo7 phosphatase complex. Predicted to be active in cytoplasm. Orthologous to human CNEP1R1 (CTD nuclear envelope phosphatase 1 regulatory subunit 1). PHENOTYPE: Conditional knockout in myeloid cells results in reduced levels of pro-inflammatory cytokines and increased susceptibility to L. monocytogenes infection. [provided by MGI curators] |