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Protein Coding Gene : Drc7 dynein regulatory complex subunit 7
Primary Identifier  MGI:2685616 Organism  mouse, laboratory
Chromosome  8 NCBI Gene Number  330830
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Involved in sperm axoneme assembly. Predicted to be located in cytoplasm. Predicted to be active in motile cilium. Is expressed in lateral ventricle choroid plexus; metencephalon floor plate; and metencephalon part of 4th ventricle choroid plexus. Orthologous to human DRC7 (dynein regulatory complex subunit 7).
PHENOTYPE: Male mice homozygous for a null allele are infertile with very few spermatozoa, immotile sperm, and abnormal sperm head and flagellum morphology. [provided by MGI curators]
  • synonyms:
  • coiled-coil domain containing 135,
  • Ccdc135,
  • Drc7,
  • dynein regulatory complex subunit 7,
  • Gm770,
  • SRG-L,
  • gene model 770, (NCBI),
  • LOC330830
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