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Protein Coding Gene : Gins3 GINS complex subunit 3
Primary Identifier  MGI:1926083 Organism  mouse, laboratory
Chromosome  8 NCBI Gene Number  78833
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Acts upstream of or within DNA replication and cellular senescence. Predicted to be located in nucleoplasm. Predicted to be part of CMG complex and GINS complex. Is expressed in cerebral cortex ventricular layer; cortical plate; and heart. Orthologous to human GINS3 (GINS complex subunit 3).
PHENOTYPE: Homozygous deletion is embryonic lethal. Homozygosity for a hypomorphic point mutation affects DNA replication and cellular senescence and leads to pre-weaning lethality. [provided by MGI curators]
  • synonyms:
  • expressed sequence AI616142,
  • AI616142,
  • GINS complex subunit 3,
  • Gins3,
  • MGI:2142596,
  • RIKEN cDNA 2700085M18 gene,
  • 2700085M18Rik,
  • Psf3
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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Function

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Homology

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Interactions

7 Pathways

Trail: ProteinCodingGene

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Gene --> Protein-Protein Interactions

Expression

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Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

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