| Primary Identifier | MGI:95792 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 14719 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables L-aspartate:2-oxoglutarate aminotransferase activity. Involved in malate-aspartate shuttle. Acts upstream of or within aspartate biosynthetic process; glutamate catabolic process to aspartate; and oxaloacetate metabolic process. Located in mitochondrion. Is active in mitochondrial matrix. Is expressed in several structures, including alimentary system; nervous system; respiratory system; sensory organ; and urinary system. Used to study early infantile epileptic encephalopathy. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 82. Orthologous to human GOT2 (glutamic-oxaloacetic transaminase 2). PHENOTYPE: Homozygosity for knockout or certain in-frame deletion or missense alleles is embryonic lethal. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
