Primary Identifier | MGI:2447160 | Organism | mouse, laboratory |
Chromosome | 8 | NCBI Gene Number | 73381 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables transcription corepressor activity. Acts upstream of or within negative regulation of DNA-templated transcription and regulation of testosterone biosynthetic process. Located in cytoplasm and nucleus. Orthologous to human CMTM2 (CKLF like MARVEL transmembrane domain containing 2). PHENOTYPE: Mice homozygous for a knock-out alleles of Cmtm2a and Cmtm2b exhibit impaired male fertility. [provided by MGI curators] |