Primary Identifier | MGI:2447162 | Organism | mouse, laboratory |
Chromosome | 8 | NCBI Gene Number | 68119 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable cytokine activity. Acts upstream of or within blastocyst hatching and positive regulation of B cell receptor signaling pathway. Located in cytoplasm and nuclear membrane. Is expressed in early conceptus and secondary oocyte. Orthologous to human CMTM3 (CKLF like MARVEL transmembrane domain containing 3). PHENOTYPE: Mice homozygous for a knock-out allele develop cardiac hypertrophy and exhibit exacerbated myocardial hypertrophy and cardiac dysfunction in response to angiotensin II infusion. [provided by MGI curators] |