| Primary Identifier | MGI:1932137 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 81877 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Enables collagen binding activity and heparin binding activity. Acts upstream of or within several processes, including collagen fibril organization; regulation of JNK cascade; and triglyceride metabolic process. Located in extracellular matrix. Is expressed in several structures, including alimentary system; genitourinary system; heart and pericardium; immune system; and nervous system. Human ortholog(s) of this gene implicated in Ehlers-Danlos syndrome; Ehlers-Danlos syndrome classic-like 1; and vesicoureteral reflux. Orthologous to several human genes including TNXB (tenascin XB). PHENOTYPE: Homozygous null mice have stretchy skin, similar to patients with human Ehlers-Danlos syndrome. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
