| Primary Identifier | MGI:1918046 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 70796 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables protein-cysteine S-palmitoyltransferase activity. Involved in several processes, including antiviral innate immune response; peptidyl-L-cysteine S-palmitoylation; and positive regulation of protein-containing complex assembly. Acts upstream of or within protein palmitoylation. Located in endosome membrane. Is expressed in several structures, including adrenal gland; central nervous system; genitourinary system; heart; and lung. Orthologous to human ZDHHC1 (zinc finger DHHC-type containing 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit lower serum cytokine levels after herpes simplex virus-1 (HSV-1) infection and are more sensitive to HSV-1-induced death. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
