Primary Identifier | MGI:88558 | Organism | mouse, laboratory |
Chromosome | 8 | NCBI Gene Number | 109660 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables peptidase activity. Acts upstream of or within proteolysis. Is expressed in brain; embryo; pancreas; and pancreas tip epithelium. Orthologous to human CTRL (chymotrypsin like). PHENOTYPE: Mice homozygous for a null allele exhibit mice exhibit reduced intrapancreatic chymotrypsin activation but normal response to induced pancreatitis. [provided by MGI curators] |