Primary Identifier | MGI:99551 | Organism | mouse, laboratory |
Chromosome | 8 | NCBI Gene Number | 12554 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables adiponectin binding activity and identical protein binding activity. Predicted to be involved in several processes, including cell-cell junction organization; positive regulation of cell population proliferation; and small GTPase-mediated signal transduction. Located in external side of plasma membrane. Is expressed in several structures, including alimentary system; appendicular skeleton; cardiovascular system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in breast cancer (multiple); lung non-small cell carcinoma; reproductive organ cancer (multiple); and urinary bladder cancer. Orthologous to human CDH13 (cadherin 13). PHENOTYPE: Mice homozygous for a null allele exhibit decreased retinal neovascularization and increased adiponectin levels. [provided by MGI curators] |