| Primary Identifier | MGI:109576 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 21341 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable RNA polymerase I core promoter sequence-specific DNA binding activity and RNA polymerase I general transcription initiation factor activity. Predicted to be involved in RNA polymerase I preinitiation complex assembly. Predicted to act upstream of or within transcription by RNA polymerase I. Part of RNA polymerase transcription factor SL1 complex. Is expressed in limb and limb mesenchyme. Orthologous to human TAF1C (TATA-box binding protein associated factor, RNA polymerase I subunit C). PHENOTYPE: Mice homozygous for a knock-out allele show embryonic lethality before implantation. In vitro, blastocysts fail to hatch from the zona pellucida and die after 3 days in culture, never forming outgrowths. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
