Primary Identifier | MGI:2142662 | Organism | mouse, laboratory |
Chromosome | 8 | NCBI Gene Number | 102193 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables protein-cysteine S-palmitoyltransferase activity. Involved in glucose import in response to insulin stimulus; peptidyl-L-cysteine S-palmitoylation; and regulation of protein localization to plasma membrane. Located in Golgi apparatus. Is expressed in central nervous system; early conceptus; and genitourinary system. Orthologous to human ZDHHC7 (zinc finger DHHC-type palmitoyltransferase 7). PHENOTYPE: Mice homozygous for a null allele appear behaviorally and physically normal and show no alterations in palmitoylation of the gamma2 subunit of GABA type A receptors (GABAARs), of GAP-43 and of the AMPA receptor subunits GluA2/3 in whole brain extracts. [provided by MGI curators] |