| Primary Identifier | MGI:1095400 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 22761 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in embryonic hemopoiesis; heart development; and negative regulation of mast cell differentiation. Acts upstream of or within several processes, including myeloid cell differentiation; regulation of chemokine production; and regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including alimentary system; central nervous system; extraembryonic component; genitourinary system; and heart. Orthologous to human ZFPM1 (zinc finger protein, FOG family member 1). PHENOTYPE: Homozygous mutants have poorly vascularized yolk sacs and small, pale livers. Mutants die between embryonic days 10.5 and 12.5 with severe anemia associated with a block in megakaryocyte development. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
