| Primary Identifier | MGI:1914427 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 67177 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA binding activity. Involved in DNA replication checkpoint signaling and regulation of DNA-templated DNA replication initiation. Acts upstream of or within regulation of nuclear cell cycle DNA replication. Located in nucleus. Is expressed in several structures, including adrenal medulla; brain ventricular layer; cerebral cortex subventricular zone; liver; and trunk mesenchyme derived from neural crest. Human ortholog(s) of this gene implicated in Meier-Gorlin syndrome 4. Orthologous to human CDT1 (chromatin licensing and DNA replication factor 1). PHENOTYPE: Mice homozygous for a small in-frame deletion in exon 2 are viable and fertile. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
