Primary Identifier | MGI:94917 | Organism | mouse, laboratory |
Chromosome | 8 | NCBI Gene Number | 13479 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables beta-lactamase activity and dipeptidase activity. Involved in several processes, including glutathione catabolic process; leukotriene metabolic process; and neutrophil chemotaxis. Predicted to be located in several cellular components, including apical part of cell; extracellular space; and nucleoplasm. Predicted to be active in plasma membrane. Is expressed in genitourinary system; incisor; and lung. Human ortholog(s) of this gene implicated in hepatoblastoma. Orthologous to human DPEP1 (dipeptidase 1). PHENOTYPE: Mice homozygous for disruption of this gene ar phenotypically normal although defects have been noted in the conversion of leukotriene D4 to leukotrience E4. [provided by MGI curators] |