Primary Identifier | MGI:1914105 | Organism | mouse, laboratory |
Chromosome | 8 | NCBI Gene Number | 66855 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable transcription corepressor activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II; regulation of protein K48-linked ubiquitination; and rescue of stalled ribosome. Located in nucleus. Is expressed in several structures, including alimentary system; bone; genitourinary system; nervous system; and skin. Orthologous to human TCF25 (transcription factor 25). PHENOTYPE: Mice homozygous for a null mutation display increased responses of the heart to induced stress. [provided by MGI curators] |