Primary Identifier | MGI:1860508 | Organism | mouse, laboratory |
Chromosome | 8 | NCBI Gene Number | 56199 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables ATP binding activity; ATP hydrolysis activity; and identical protein binding activity. Involved in heme biosynthetic process and positive regulation of erythrocyte differentiation. Located in mitochondrial inner membrane. Is expressed in several structures, including cardiovascular system; genitourinary system; liver and biliary system; musculoskeletal system; and nervous system. Orthologous to human ABCB10 (ATP binding cassette subfamily B member 10). PHENOTYPE: Mice homozygous for a knock-out allele exhibit embryonic lethality. Mice heterozygous for this allele exhibit increased response to ischemia and reperfusion. [provided by MGI curators] |