Primary Identifier | MGI:1915202 | Organism | mouse, laboratory |
Chromosome | 8 | NCBI Gene Number | 67952 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable mitochondrion targeting sequence binding activity; protein-transporting ATPase activity; and unfolded protein binding activity. Predicted to contribute to protein transmembrane transporter activity. Predicted to be involved in protein import into mitochondrial matrix and tRNA import into mitochondrion. Located in migrasome; mitochondrial envelope; and sperm midpiece. Is active in cell periphery. Is expressed in several structures, including central nervous system; genitourinary system; heart; and liver. Orthologous to human TOMM20 (translocase of outer mitochondrial membrane 20). PHENOTYPE: Mice homozygous for a knock-out allele show complete embryonic lethality prior to organogenesis. In vitro, blastocysts do not hatch from the zona pellucida or form outgrowths. [provided by MGI curators] |