Primary Identifier | MGI:1922566 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 75316 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable identical protein binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in cytosol; microtubule cytoskeleton; and nucleolus. Predicted to be part of RNA polymerase transcription factor SL1 complex. Predicted to be active in nucleoplasm. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and sensory organ. Orthologous to human TAF1D (TATA-box binding protein associated factor, RNA polymerase I subunit D). PHENOTYPE: Mice homozygous for a knock-out allele show embryonic lethality before implantation. In vitro, embryos fail to hatch from the zona pellucida and die after 3 days in culture, never forming outgrowths. [provided by MGI curators] |