Primary Identifier | MGI:1914167 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 66917 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables ADP binding activity; ATP binding activity; and zinc ion binding activity. Involved in several processes, including chaperone-mediated protein folding; negative regulation of Rho-dependent protein serine/threonine kinase activity; and regulation of centrosome duplication. Is expressed in brain; olfactory epithelium; trigeminal ganglion; and vomeronasal organ. Used to study chronic myeloid leukemia. Orthologous to human CHORDC1 (cysteine and histidine rich domain containing 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit embryonic lethality before somite formation with decreased proliferation and increased apoptosis of cultured inner cell masse cells. [provided by MGI curators] |