Primary Identifier | MGI:1354738 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 30843 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within ubiquitin-dependent protein catabolic process. Located in cytoplasm. Part of ubiquitin ligase complex. Is expressed in cerebral cortex ventricular layer; chorioallantoic placenta; cortical plate; decidua; and embryo. Orthologous to human FBXL12 (F-box and leucine rich repeat protein 12). PHENOTYPE: Mice homozygous for a knock-out allele exhibit partial postnatal lethality, growth retardation, small placenta, absent gastric milk in mice that die and abnormal placental. [provided by MGI curators] |