| Primary Identifier | MGI:1929470 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 54721 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable growth hormone receptor binding activity; non-membrane spanning protein tyrosine kinase activity; and type 1 angiotensin receptor binding activity. Involved in cell population proliferation and positive regulation of T cell proliferation. Predicted to be located in cytoplasm and nucleus. Predicted to be active in cytosol. Used to study obesity. Human ortholog(s) of this gene implicated in immunodeficiency 35. Orthologous to human TYK2 (tyrosine kinase 2). PHENOTYPE: Homozygous mutant mice are viable and fertile, but differ from wild-type with respect to interleukin 12 mediated T cell function. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
