Primary Identifier | MGI:105387 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 12581 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables protein kinase binding activity. Acts upstream of or within negative regulation of cell cycle G1/S phase transition and sensory perception of sound. Part of cyclin D2-CDK4 complex. Is expressed in several structures, including central nervous system; hemolymphoid system gland; liver; musculature; and trigeminal nerve. Orthologous to human CDKN2D (cyclin dependent kinase inhibitor 2D). PHENOTYPE: Both female and male homozygous null mice are fertile in spite of testicular atrophy and increased male germ cell apoptosis due to delayed meiosis. [provided by MGI curators] |