| Primary Identifier | MGI:1931441 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 60507 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables tRNA-guanosine(34) queuine transglycosylase activity. Involved in tRNA-guanine transglycosylation. Located in cytoplasmic side of mitochondrial outer membrane and nucleus. Part of protein-containing complex. Colocalizes with mitochondrion. Is expressed in several structures, including alimentary system; facial bone primordium; nervous system; respiratory system; and urinary system. Orthologous to human QTRT1 (queuine tRNA-ribosyltransferase catalytic subunit 1). PHENOTYPE: Mice heterozygous or homozygous for a gene trap allele exhibit reduced phenylalanine conversion to tyrosine and reduced cell levels of queuosine-modified tRNA. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
