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Protein Coding Gene : Dock6 dedicator of cytokinesis 6
Primary Identifier  MGI:1914789 Organism  mouse, laboratory
Chromosome  9 NCBI Gene Number  319899
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in regulation of Rho protein signal transduction. Predicted to be located in perinuclear region of cytoplasm. Predicted to be active in cytosol. Is expressed in several structures, including forelimb bud; head mesenchyme derived from neural crest; limb; nervous system; and spleen. Human ortholog(s) of this gene implicated in Adams-Oliver syndrome. Orthologous to human DOCK6 (dedicator of cytokinesis 6).
  • synonyms:
  • 4931431C02Rik,
  • RIKEN cDNA 2410095B20 gene,
  • Dock6,
  • RIKEN cDNA 4931431C02 gene,
  • C330023D02Rik,
  • dedicator of cytokinesis 6,
  • MGI:2442941,
  • RIKEN cDNA C330023D02 gene,
  • 2410095B20Rik,
  • mKIAA1395,
  • MGI:1924030
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Features --> Cross References

Genome

Sequence Feature Displayer

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

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Interactions

8 Pathways

Trail: ProteinCodingGene

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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