| Primary Identifier | MGI:1335094 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 235072 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Enables AP-3 adaptor complex binding activity. Acts upstream of or within several processes, including D-glucose import across plasma membrane; cortical cytoskeleton organization; and plasma membrane bounded cell projection organization. Located in axon terminus; cell body; and septin cytoskeleton. Part of septin complex. Is active in cytoplasm; presynaptic membrane; and vesicle. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human SEPTIN7 (septin 7). PHENOTYPE: Mice homozygous for a conditional allele activated in neurons exhibit reduced axon and dendrite length and complexity. Mice homozygous for a knock-out allele die prior to E10.5. [provided by MGI curators] |