Primary Identifier | MGI:1917656 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 69091 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in regulation of neurotransmitter receptor localization to postsynaptic specialization membrane and retrograde transport, endosome to Golgi. Acts upstream of or within cellular response to type II interferon. Located in early endosome; late endosome; and phagocytic vesicle. Part of retromer complex. Is active in glutamatergic synapse; postsynaptic early endosome; and postsynaptic recycling endosome. Is expressed in several structures, including central nervous system; dorsal root ganglion; male reproductive system; sensory organ; and urinary system. Orthologous to human VPS26B (VPS26 retromer complex component B). PHENOTYPE: Mice homozygous for a knock-out allele exhibit normal behavior, growth, and health. [provided by MGI curators] |