Primary Identifier | MGI:2384574 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 235135 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to be involved in innate immune response. Predicted to be located in Golgi apparatus; endosome membrane; and lysosomal membrane. Is expressed in central nervous system; ganglia; gut; olfactory epithelium; and vibrissa. Orthologous to human TMEM45B (transmembrane protein 45B). PHENOTYPE: Mice homozygous for a null allele exhibit reduced long-lasting mechanical pain hypersensitivity in a CFA-induced inflammatory pain model or following surgical tissue incision. [provided by MGI curators] |