| Primary Identifier | MGI:1925037 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 235283 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables cholesterol binding activity; cholesterol transfer activity; and phospholipid binding activity. Involved in cellular response to cholesterol and cholesterol homeostasis. Located in endoplasmic reticulum membrane; endoplasmic reticulum-plasma membrane contact site; and plasma membrane. Is expressed in several structures, including adrenal medulla; brain; retina; and testis. Orthologous to human GRAMD1B (GRAM domain containing 1B). PHENOTYPE: Mice homozygous for a knock-out allele show altered adrenal cholesterol homeostasis due to an inability to transport cholesterol from plasma membrane to the endoplasmic reticulum. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
