Primary Identifier | MGI:1920078 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 72828 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables phosphoprotein binding activity and protein tyrosine phosphatase activity. Involved in regulation of osteoclast differentiation. Acts upstream of or within several processes, including collagen-activated tyrosine kinase receptor signaling pathway; negative regulation of bone resorption; and negative regulation of platelet aggregation. Predicted to be located in nucleus. Predicted to be active in cytoplasm. Is expressed in several structures, including central nervous system; incisor; limb; nasal cavity epithelium; and retina. Orthologous to human UBASH3B (ubiquitin associated and SH3 domain containing B). PHENOTYPE: Mice homozygous for a knock-out allele are viable, fertile, developmentally normal, and do not display any obvious phenotypic abnormalities. [provided by MGI curators] |