Primary Identifier | MGI:98747 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 21838 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables integrin binding activity. Involved in several processes, including integrin-mediated signaling pathway; positive regulation of focal adhesion assembly; and retinal cone cell development. Located in dendrite; external side of plasma membrane; and membrane raft. Is active in glutamatergic synapse; postsynapse; and presynapse. Is expressed in several structures, including appendicular skeleton; hemolymphoid system; nervous system; retina; and urinary system. Orthologous to human THY1 (Thy-1 cell surface antigen). PHENOTYPE: Homozygous null mice are viable, fertile, and display no abnormalities in the brain and spinal cord, have normal axonal development and regeneration and no behavioral abnormalities. Long term potentiation is inhibited in the dentate gyrus. [provided by MGI curators] |