Primary Identifier | MGI:1933966 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 84004 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable laminin receptor activity. Predicted to be involved in angiogenesis and positive regulation of cell migration. Predicted to act upstream of or within heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules. Predicted to be located in external side of plasma membrane and extracellular space. Predicted to be active in plasma membrane. Is expressed in several structures, including adipose tissue; extraembryonic component; genitourinary system; gut; and nervous system. Orthologous to human MCAM (melanoma cell adhesion molecule). PHENOTYPE: Mice homozygous for a conditional allele activated in endothelial cells exhibit impaired VEGF-induced angiogenesis in Matrigel. [provided by MGI curators] |