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Protein Coding Gene : Mpzl3 myelin protein zero-like 3
Primary Identifier  MGI:2442647 Organism  mouse, laboratory
Chromosome  9 NCBI Gene Number  319742
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Acts upstream of or within extracellular matrix organization and hair cycle. Predicted to be located in membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in lung cancer. Orthologous to human MPZL3 (myelin protein zero like 3).
PHENOTYPE: Mice homozygous for a spontaneous allele have a rough coat that becomes brittle and oily with age, and display stunted growth, cyclic and progressive hair loss, hyperplastic epidermis, abnormal hair follicles, myocardial degeneration, and reduced collagen and elastin content in the skin and heart. [provided by MGI curators]
  • synonyms:
  • MGD-MRK-13802,
  • myelin protein zero-like 3,
  • MGI:97880,
  • MGI:98207,
  • ruf,
  • rough coat,
  • Mpzl3,
  • rc,
  • MGI:1918661,
  • RIKEN cDNA 5430427F17 gene,
  • RIKEN cDNA A530065I17 gene,
  • rough fur,
  • 5430427F17Rik,
  • A530065I17Rik,
  • MGD-MRK-14253
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