| Primary Identifier | MGI:2442293 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 235323 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in several processes, including intracellular signal transduction; protein deubiquitination involved in ubiquitin-dependent protein catabolic process; and response to ionizing radiation. Predicted to be located in nuclear body. Predicted to be part of protein-containing complex. Predicted to be active in cytosol and nucleus. Is expressed in early embryo; foregut; heart; and skeletal musculature. Orthologous to human USP28 (ubiquitin specific peptidase 28). PHENOTYPE: Mice homozygous for a knock-out allele are viable and fertile and exhibit slightly decreased spleen weight and splenocyte number but show neither major signaling defects in DNA damage response nor developmental defects indicative of impaired double-strand break metabolism. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
